Tag Archive for: drugs

Would you take part in a clinical trial? UK Ulcerative Colitis patients needed

Clinical trials are research studies that look into treatments for certain illnesses and gather information for future reference to further knowledge of those illnesses.

I am working with clinical research company, Quotient Clinical as they have a study for people with Ulcerative Colitis and are looking for participants.  The purpose of this study is to see how a study drug is taken up by the body, the drug is being developed for the treatment of pain and diarrhoea in Ulcerative Colitis patients.

People choose to take part in clinical trials for many reasons, it helps increase understanding of their condition and it may benefit others in the future.  As we know, there is no cure for Ulcerative Colitis and the current treatments can be very harsh on our bodies, I am a strong advocate for research and development of treatments and studies like this are a good way to seek out a better way to treat our symptoms and illness.

This study requires a few visits to their unit in Nottingham, firstly an initial screening appointment lasting 4 hours.  Then there is a 2 night residential stay in a unit, two further brief 30 minute visits for sampling and then a 30 minute final follow up visit.  That’s quite a lot of commitment, I know, but the group do pay £915 plus a travel allowance for your time and effort and you will have the knowledge that your participation will help future sufferers.

Studies like this aren’t for everyone, you need to think about your own personal circumstances, but for some people it will be a positive experience where they can potentially help future patients.

sam cleasby sheffield blogger disability

The NHS website give some advice on taking part in studies;

Advantages of being in a clinical trial

  • The main reason for carrying out trials is to assess whether one treatment is better than another
  • Trials are very important in helping find better treatments. By being involved in a trial, you’ll obtain information and evidence that may be helpful to you in the future, as well as helping the NHS provide people with the best possible standard of care

Disadvantages of being in a clinical trial

  • It’s possible you’ll experience unexpected side effect
  • You need to commit time to completing the study

Interested? Or know someone who might be?

The requirements are that you are aged over 18 years old, you must have been diagnosed with Ulcerative Colitis at least 4 months ago and have a BMI between 16 and 35.  You must not have taken part in a clinical trial within the past three month or donated blood in the three months before the start of trial.

There are various dates in September and October and dates are flexible

For more information, go to the Quotient Clinical website and fill in the application form or contact them on 0330 303 5000 or email 


clinical study ulcerative colitis


Love Sam xx


Disclaimer: This is a sponsored post. From time to time, I work with companies and groups who pay me to showcase their products or events.  This helps me fund this website and keep it running.  I only work with companies whom I believe are of interest and beneficial to my lovely readers.

Codiene, Jpouch and doctors with funny names

I saw a new dr on Thursday, a registrar on the team of fabulous medics who have been looking after me. As you may know, my surgeon is called Mr Brown, we do laugh that he has an appropriate name for a bum doctor… Well, the new one was called Dr Liu. Dr Loo?! Are they kidding?

When they become a doctor do they choose the funniest name they can think of that relates to their speciality? Did I mention my friend’s dad (he has an ostomy too) whose doctor is Mr Butt!

Or is it like Harry Potter’s sorting hat? When you start medical school do they match your name to the most appropriate category?

Anyway Dr Liu was very nice, he talked through my camera test which showed a very small amount of inflammation but not enough to be causing me so many problems. The Coeliac test hasn’t come back yet but all other blood tests are normal. This is great to know there’s nothing majorly wrong but a little annoying as it means there is no easy treatment.

I am going to the toilet around 15 times a day, sometimes as many as 20, I have talked before about how it is normal for someone with a pouch to go multiple times a day but this is very excessive. Since the op I take Imodium every day to slow the output.

The doctors have added in two more drugs to slow everything down. The first is fybogel which thickens the stool and therefore makes the passage through the body slower.

The other new drug is codiene. Though it’s used as a painkiller, a side effect of codiene is constipation and so I’ve been put on quite a bit of it. I’m now taking 4 Imodium, 2 fybogel and 8 codiene a day. I wasn’t sure at all about taking so much of a string painkiller but after 2 days it seems to be working!

On Friday I went to the toilet just 7 times in 24 hours and then amazingly I slept through the night last night!!!!


I can’t describe how good it feels to have had a proper nights sleep after so long of waking at least a couple times a night.

The only issue is that codiene are strong painkillers. I’m feeling very sleepy and foggy headed and so the codiene isn’t going to work long term for me as I don’t feel able to drive or do much at all when I’ve had the tablets.

The plan is to try this combo for 6 weeks then go back and see the team. If things aren’t settled by then, we will reevaluate.

Thanks so much for the lovely messages

Sam xx